Children's Hospital Colorado
A close-up view of an IV inserted into a baby's arm that's wearing lime green bandages
Center for cancer and blood disorders

Hematology and Oncology Resources for Healthcare Professionals

At Children's Hospital Colorado, we're committed to helping all healthcare professionals improve the quality of life for children with cancers and blood disorders. Get the latest in hematology and oncology information to better your practice and learn about innovation within our various programs.

A medical provider at Children's Hospital Colorado talks with a toddler and her family in the Center for Cancer and Blood Disorders.

Referral Guidelines

These referral guidelines provide useful information to assist referring physicians in the evaluation and management of pediatric patients. Use these to help determine the best approach to the treatment of your patients, or to help determine when to refer to a specialist.

Hematology referral guidelines (.pdf)

Research articles and summaries

Research article

More than anything else on the medical horizon, CAR-T cell therapy stands poised to alter cancer treatment. But it's not there yet.

Clinical trial

The goal of the study is to identify biologically rational therapeutics for the medical treatment of adamantinomatous craniopharyngioma by confirming the overexpression of specific molecules and ultimately improving treatment for patients with this rare tumor.

Diagnosis
Patients with the diagnosis or clinical suspicion of craniopharyngioma in whom planned clinical management will include tissue sampling
Age
0-21 years of age

Professional resources

Charting Pediatrics is a weekly podcast for pediatric healthcare providers. In this series, specialists from Children’s Hospital Colorado examine the latest treatments for the most common complaints in pediatric medicine. Listen and subscribe on Spotify, iTunes and Google Play.

 

CAR-T Cellular Therapy for Leukemia

In this episode, Terry Fry, MD, and Mike Verneris, MD, explore the topic of cellular therapy for the treatment of pediatric cancers.

 

Vascular Malformations in Pediatric Primary Care

In this episode, Taizo Nakano, MD, Medical Director of the Vascular Anomalies Center at Children's Colorado, discusses the most common vascular anomalies in the primary care setting.

Hematology and Oncology news

JAMA

Association of Matched Sibling Donor Hematopoietic Stem Cell Transplantation with Transcranial Doppler Velocities in Children with Sickle Cell Anemia

January 23, 2019

Among children with SCA requiring chronic transfusion because of persistently elevated TCD velocities, MSD-HSCT was significantly associated with lower TCD velocities at 1 year compared with standard care. Further research is warranted to assess the effects of MSD-HSCT on clinical outcomes and over longer follow-up.

Journal of Clinical Oncology

Outcome of Children with Hypodiploid Acute Lymphoblastic Leukemia: A Retrospective Multinational Study

January 22, 2019

MRD-stratified treatments improved the outcome for children with hypodiploid ALL. Allogeneic transplantation did not significantly improve outcome overall and, in particular, for patients who achieved MRD-negative status after induction.

JAMA Oncology

Association of Combined Modality Therapy vs. Chemotherapy Alone with Overall Survival in Early-Stage Pediatric Hodgkin Lymphoma

January 3, 2019

In this study, pediatric patients with early-stage HL receiving CMT experienced improved overall survival 5 years after treatment. There is a nationwide decrease in the use of CMT, perhaps reflecting the bias of ongoing clinical trials designed to avoid consolidation radiotherapy. This study represents the largest data set to date examining the role of CMT in pediatric HL.

Stay informed

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