At the Center for Cancer and Blood Disorders, discoveries from our laboratories are changing the way care is delivered for pediatric hematology, oncology and bone marrow transplants.
Our scientists are recognized as national leaders in basic and clinical science research and have funding to support their research from numerous national hematology and oncology foundations.
Our oncology and hematology advances
We believe that state-of-the-art treatment for pediatric cancer and blood disorders typically includes enrollment in a clinical trial. In fact, research shows that children who participate in clinical trials have better survival rates than children who do not.
Our physicians and nurses collaborate with laboratory researchers to find new cures and better cancer treatment. Some of our team's most significant advancements include:
- Our physicians discovered new genes important in cancer, and we are using this knowledge to develop new drugs and treatment protocols that more specifically and effectively kill cancer cells. We identified new cancer targets for brain cancer, acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).
- Lia Gore, MD, the leader of our Experimental Therapeutics Program, co-founded the Pediatric Oncology Experimental Therapeutics Investigators Consortium (POETIC), which often expands local clinical trials to children and adolescents across the country.
- Clinical research by a team at our Hemophilia and Thrombosis Center revolutionized the care of children with hemophilia. The researchers transitioned the focus from treatment to prevention of life-threatening and debilitating bleeding episodes through regular home administration of clotting factors.
- Hematology researchers identified the gene that causes grey platelet syndrome, a discovery that will now be used to set the foundation of care for newly diagnosed patients.
What our cancer and blood disorder research means for kids
Physicians at the Center for Cancer and Blood Disorders have a variety of interests in clinical, translational and laboratory research. Our major focus areas include:
- Clinical trials for children with all types of cancer
- New cancer therapies
- Sickle cell disease
- Hemophilia and clotting disorders
- Redirecting the immune system
- Different modes of bone marrow transplantation
Our translational and basic laboratory research includes:
- Pediatric leukemia and neuro-oncology biology and genetics
- New molecularly targeted therapies for various types of cancer
- Genetic studies of von Willebrand disease
- Immunotherapy with T cells and NK cells
Our faculty collaborates with international consortiums, laboratory researchers and the University of Colorado Cancer Center to find new cures and better cancer treatments for children.
We also participate in every major pediatric cooperative group for cancer and blood disorders, including:
Learn more about the Center for Cancer and Blood Disorders.